A comparison of a new alcohol-free 0.2% chlorhexidine oral rinse to an established 0.2% chlorhexidine rinse with alcohol for the control of dental plaque accumulation
Int J Dent Hygiene DOI: 10.1111/idh.12182 , , , , . A comparison of a new alcohol-free 0.2% chlorhexidine oral rinse to an established 0.2% chlorhexidine rinse with alcohol for the control of dental plaque accumulation.
Abstract
Objectives
To
compare the clinical efficacy of two formulations (alcohol and alcohol
free) of 0.2% chlorhexidine (CHX) rinses on plaque, gingivitis and
discoloration of teeth.
Methods
This
double-blind crossover study consisted of one group of 10 volunteer
dental students that followed two 21-day experimental gingivitis test
periods. During these periods, the subjects abstained from oral hygiene
except for the oral rinse provided. The study started after an initial
two-week preparation programme that included a professional prophylaxis
and repeated oral hygiene instructions. This was repeated for the 14-day
washout period between the two rinses, including prophylaxis as per the
first stage of the study. A calibrated examiner performed the clinical
measurements at the beginning (baseline) and end of each study stage.
The presence and amount of plaque were recorded using the Silness and
Löe plaque index (PI) and gingival inflammation by the gingival index
(GI) while the discoloration index (DI) was recorded on the buccal and
lingual surfaces of the six anterior teeth of both the mandible and
maxilla.
Results
Mean
PI increased similarly for both solutions; however, the differences
between initial and final values were statistically significant only for
CHLOREL®. Similarly, the mean values for the GI showed small
increases over the course of the study periods, but not statistically
significant for either solution. The mean DI increased significantly for
both solutions. Regarding the comparison of the initial and final
values between the solutions, per index, no statistically significant differences were observed.
Conclusion
The non-alcoholic chlorhexidine rinse had comparable levels of action as the generally recognized gold standard alcoholic rinse.
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