LIGHT protein: A novel gingival crevicular fluid biomarker associated with increased probing depth after periodontal surgery
First published: 23 February 2024 https://doi.org/10.1111/jcpe.13964 Abstract Aim To evaluate the protein profiles in gingival crevicular fluid (GCF) in relation to clinical outcomes after periodontal surgery and examine if any selected proteins affect the mRNA expression of pro-inflammatory cytokines in human gingival fibroblasts. Materials and Methods This exploratory study included 21 consecutive patients with periodontitis. GCF was collected, and the protein pattern ( n = 92) and clinical parameters were evaluated prior to surgery and 3, 6 and 12 months after surgery. Fibroblastic gene expression was analysed by real-time quantitative polymerase chain reaction.
