Saturday, June 29, 2013

Treatment of salivary gland hypofunction by transplantation with dental pulp cells

Archives of Oral Biology
Volume 58, Issue 8 , Pages 935-942, August 2013



This study aimed to establish a mouse model in which dental pulp cells (DPCs) could be used as a cell source for the treatment of salivary gland hypofunction.


DPCs were isolated from green fluorescent protein (GFP)-expressing mice and were differentiated into dental pulp endothelial cells (DPECs). DPEC behaviour was studied in vitro and in vivo to investigate their capacity to participate in neovascularisation. For in vivo assessment, a combination of DPECs and Matrigel was subcutaneously injected into nude mice. Two weeks after injection, Matrigel plugs were analysed for CD31 and GFP. Furthermore, both submandibular glands of the irradiated mice were injected with DPECs. Eight weeks after irradiation, the effect of DPECs on saliva secretion was evaluated by measuring amounts of saliva secretion.


DPECs showed typical endothelial morphology, including a cobblestone appearance. RT-PCR analysis of DPECs showed positive expression of CD31, foetal liver kinase-1, vascular–endothelial–cadherin, vascular endothelial growth factor-A and von Willebrand factor. DPECs reorganised into tube-like structures on Matrigel after 24h in vitro. Positive merged staining for both CD31 and GFP was observed in the tube-like structures, representative of the injected DPECs. The average saliva flow rate in mice treated with DPECs was significantly higher than that observed in mice treated with PBS (P=0.0452).


Our results show that radiation-induced salivary hypofunction is partially reverted following transplantation of DPECs. We established a mouse model in which DPCs could be used as a cell source for the treatment of salivary gland hypofunction.

Friday, June 28, 2013

Validity of Caries Risk Assessment Programs in Preschool Children

Available online 19 June 2013



Various programs have been developed for caries risk assessment (CRA). Nevertheless, scientific evidence on their validity is lacking. This study aimed to compare the validity of 4 CRA programs (CAT, CAMBRA, Cariogram, and NUS-CRA) in predicting early childhood caries.


A total of 544 children aged 3 years underwent oral examination and biological tests (saliva flow rate, salivary buffering capacity and abundance of cariogenic bacteria mutans Streptococci and Lactobacilli). Their parents completed a questionnaire. Children's caries risk was predicted using the 4 study programs without biological tests (screening mode) and with biological tests (comprehensive mode). After 12 months, caries increment in 485 (89%) children was recorded and compared with the baseline risk predictions.


Reasoning-based programs (CAT and CAMBRA screening) had high sensitivity (≥93.8%) but low specificity (≦43.6%) in predicting caries in children. CAMBRA comprehensive assessment reached a better balance (sensitivity/specificity of 83.7%/62.9%). Algorithm-based programs (Cariogram and NUS-CRA) generated better predictions. The sensitivity/specificity of NUS-CRA screening and comprehensive models were 73.6%/84.7% and 78.1%/85.3%, respectively, higher than those of the Cariogram screening (62.9%/77.9%) and comprehensive assessment (64.6%/78.5%). NUS-CRA comprehensive model met the criteria for a useful CRA tool (sensitivity + specificity≥160%), while its screening model approached that target.


Our results supported algorithm-based approach of caries risk modelling and the usefulness of NUS-CRA in identifying children susceptible to caries.

Clinical significance

This prospective study provided evidence for practitioners to choose tools for assessing children's caries risk, so that prevention measures can be tailored and treatment plan can be optimized.

Thursday, June 27, 2013

Darby Dental Teams Up with Students from Molloy College to Provide Disaster Relief to Those Affected by Massive Tornado

Various Supplies Sent to Oklahoma Dental Association

Jericho, NY (June 23, 2013) – In an effort to provide much-needed assistance to Oklahoma tornado victims, Darby Dental Supply, LLC, the largest all-telesales national distributor of dental merchandise, joined forces with students from the Molloy College National Student Speech Language and Hearing Association (NSSLHA) and Molloy American Red Cross Club to contribute a large quantity of supplies to the Oklahoma Dental Association. 

Darby provided items such as toothbrushes, toilet tissue, garbage bags and respirator masks to the Oklahoma Dental Association who in turn distributed them to local residents affected by the devastation of the recent tornado. In addition, students from the Molloy College National Student Speech Language and Hearing Association and Molloy American Red Cross Club worked directly with the Oklahoma Red Cross to allocate the items to areas most in need after the storm.

With assistance from the students at Molloy College, Darby was able to provide the supplies toward the recovery effort in a mere two days following the disaster. “We feel it’s our duty to support communities affected by natural disaster in any way that we can,” remarked Liz Meyers, Vice President Marketing & Purchasing for Darby Dental Supply.  “Providing supplies to those affected by the tornado is the least we can do. Our multi-faceted partnership with the students at Molloy College is a perfect extension of our philanthropic efforts that allow us to do even more nationwide."

In the recent years, Darby has adopted a “think globally, act locally” philanthropic philosophy, and has encouraged employees who want to help those affected by the tornado to make a donation to their local Red Cross chapter or the national Red Cross efforts in Oklahoma. 

Darby Dental Supply’s past diverse philanthropic efforts include both local and international relief efforts. Most recently, the company placed an emphasis on local Long Island residents who were affected by Hurricane Sandy, as well as providing numerous contributions to U.S. military troops deployed overseas. In addition, Darby provided much-needed medical supplies to a makeshift shelter in Kesennuma, Japan that was devastated by an earthquake and tsunami, and throughout the years, the company has supported various programs sponsored by Physicians for Peace within the United States and internationally.

About Darby Dental Supply, LLC

For over 65 years, family-owned and -operated Darby Dental Supply, LLC has been breaking new ground as the largest all-telesales national distributor of dental merchandise to office-based practitioners in the United States. Through strategic distribution points, the company fulfills over one million shipments per year from leading manufacturers of dental products and equipment.

Darby is equally committed to providing superior value to the dental professional. All Darby Personal Account Managers have successfully completed a comprehensive regimen of product training and have instant access to their clients’ purchase histories and preferences. Alerting them to manufacturer specials, exclusive offers and even processing product rebates on their behalf, Darby reps work with their clients as strategic partners in helping to reduce fixed costs, save money and continue to grow their business. Honoring a “one customer at a time” philosophy for more than six decades has established Darby Dental Supply as one of the largest, most trusted dental distributors in the nation. For more information, visit

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Wednesday, June 26, 2013

The Jaw Is Also A Casualty When Bacterium Causes Gum Disease

The newly discovered bacterium that causes gum disease delivers a one-two punch by also triggering normally protective proteins in the mouth to actually destroy more bone, a University of Michigan study found.

Scientists and oral health care providers have known for decades that bacteria are responsible for periodontitis, or gum disease. Until now, however, they hadn't identified the bacterium.

"Identifying the mechanism that is responsible for periodontitis is a major discovery," said Yizu Jiao, a postdoctoral fellow at the U-M Health System, and lead author of the study appearing in the recent issue of the journal Cell Host and Microbe.

Jiao and Noahiro Inohara, research associate professor at the U-M Health System, worked with William Giannobile, professor of dentistry, and Julie Marchesan, formerly of Giannobile's lab.

The study yielded yet another significant finding: the bacterium that causes gum disease, called NI1060, also triggers a normally protective protein in the oral cavity, called Nod1, to turn traitorous and actually trigger bone-destroying cells. Under normal circumstances, Nod1 fights harmful bacterium in the body.

"Nod1 is a part of our protective mechanisms against bacterial infection. It helps us to fight infection by recruiting neutrophils, blood cells that act as bacterial killers," Inohara said. "It also removes harmful bacteria during infection. However, in the case of periodontitis, accumulation of NI1060 stimulates Nod1 to trigger neutrophils and osteoclasts, which are cells that destroy bone in the oral cavity."

Giannobile, who also chairs the Department of Periodontics and Oral Medicine at the U-M School of Dentistry, said understanding what causes gum disease at the molecular level could help develop personalized therapy for dental patients.

"The findings from this study underscore the connection between beneficial and harmful bacteria that normally reside in the oral cavity, how a harmful bacterium causes the disease, and how an at-risk patient might respond to such bacteria," Giannobile said.

Tuesday, June 25, 2013

Henry Schein Opens Its Disaster Relief Hotline To Support Customers Affected By The Floods In Calgary And Southern Alberta

MELVILLE, N.Y., June 24, 2013 /PRNewswire/ -- Henry Schein Canada, the Canadian Dental business of Henry Schein, Inc. (NASDAQ: HSIC), today announced that it has opened the Henry Schein Disaster Relief Hotline for dentists who experience operational, logistical, or financial issues as a result of the devastating floods in Calgary and Southern Alberta, Canada. The toll-free number for all Henry Schein customers – 800-999-9729 – is operational from 7 a.m. to 7 p.m. CDT.
"We are so saddened to see the devastating impact that these terrible floods are having on the Calgary and Southern Alberta communities," said Cy Elborne, President, Henry Schein Canada. "We are anxious for our customers to know that we are here to help, and encourage practitioners to call our disaster relief hotline." 
Henry Schein Canada serves dental practitioners in 14 locations across Canada, including Halifax, NS; Saint John, NB; Vancouver, BC, Victoria, BC; London, ON; Ottawa, ON: Niagara-on-the-Lake, ON; Toronto, ON; Calgary, AB; Edmonton, AB; Regina, SK; Winnipeg, MB: Montreal, QC; Quebec City, QC.

About Henry Schein, Inc.Henry Schein, Inc. is the world's largest provider of health care products and services to office-based dental, medical and animal health practitioners. The Company also serves dental laboratories, government and institutional health care clinics, and other alternate care sites. A Fortune 500® Company and a member of the NASDAQ 100® Index, Henry Schein employs more than 15,500 Team Schein Members and serves more than 775,000 customers.
The Company offers a comprehensive selection of products and services, including value-added solutions for operating efficient practices and delivering high-quality care. Henry Schein operates through a centralized and automated distribution network, with a selection of more than 96,000 branded products and Henry Schein private-brand products in stock, as well as more than 110,000 additional products available as special-order items. The Company also offers its customers exclusive, innovative technology solutions, including practice management software and e-commerce solutions, as well as a broad range of financial services.
Headquartered in Melville, N.Y., Henry Schein has operations or affiliates in 25 countries. The Company's sales reached a record $8.9 billion in 2012, and have grown at a compound annual rate of 17 percent since Henry Schein became a public company in 1995. For more information, visit the Henry Schein Web site at

Monday, June 24, 2013

Colgate Oral Pharmaceuticals Introduces New and Improved* PreviDent® Varnish Formula

New, Enhanced Formula for PreviDent® 5% Sodium Fluoride Varnish Provides
Greater Enamel Fluoride Uptake 1

New York, NY (June 21, 2013) – Colgate Oral Pharmaceuticals, a subsidiary of Colgate-Palmolive Company, introduces a new and improved formula for its Colgate PreviDent® Varnish 5% Sodium Fluoride. The high-fluoride in-office treatment now contains advanced technology for greater enamel fluoride uptake.1 

Colgate PreviDent® Varnish with 5% sodium fluoride, the equivalent of 22,600 ppm fluoride provides greater enamel fluoride uptake vs. the leading varnish competitor brand** with:

  • Four times greater fluoride uptake into lesioned enamel1
  • Three times greater fluoride uptake into sound enamel1

Moreover, the new formulation provides a smooth, even and quick application, and dries to a natural enamel color.

“Switching to PreviDent® Varnish was the best decision I could have made for my patients,” said Maria Perno Goldie, RDH MS, Current President, International Federation of Dental Hygienists
and Past President of the ADHA. “They love the flavors and the transparency after I apply it.”

Ideal for both children and adults, PreviDent® Varnish contains 22,600 ppm fluoride which has been shown to provide effective dentin hypersensitivity relief2-4. It sets rapidly on contact with saliva for patient comfort and compliance. PreviDent® Varnish also contains xylitol.   

“The new formula of PreviDent® Varnish offers a substantial advantage over the leading fluoride varnish,” remarked Dr. Barbara Shearer, BDS MDS PhD, Director of Scientific Affairs, Colgate Oral Pharmaceuticals. “Our optimized in-office fluoride treatment formula provides significant fluoride uptake while being aesthetically pleasing. These attractive features combined with a great taste make PreviDent® Varnish a pleasure for both the dental professional and the patient.” 

PreviDent® Varnish is currently available in two great tasting flavors (Mint & Raspberry) and is conveniently packaged in ready-to-use unit doses (0.4mL) with disposable brushes.   

For more information, please visit 

*Compared to original Colgate® PreviDent® Fluoride Varnish in lesioned enamel
** Versus 3M Vanish Varnish


  1. Data on file; Colgate-Palmolive 2012
  2. Gaffar A. Treating hypersensitivity with fluoride varnishes. Compend Contin Dent Educ 1998; 19:1089-97.
  3. Clark DC, Hanley JA, Geoghegan S, Vinet D. The effectiveness of a fluoride varnish and a desensitizing toothpaste in treating dentinal hypersensitivity. J Periodontal Res 1985; 20(2): 212-219.
  4. Ritter AV, de L Diaz W, Miguez P, Caplan DJ, Swift EJ Jr. Treating cervical hypersensitivity with fluoride varnish: a randomized clinical study. J Am Dent Assoc 2006; 137(7): 1013-1020.

About Colgate Oral Pharmaceuticals
Colgate Oral Pharmaceuticals is a subsidiary of Colgate-Palmolive, a consumer products company, and a leader in the oral care market with both over-the-counter and therapeutic professional products. For more information, please visit 

About Colgate-Palmolive
Colgate-Palmolive is a leading global consumer products company, tightly focused on Oral Care, Personal Care, Home Care and Pet Nutrition. Colgate sells its products in over 200 countries and territories around the world under such internationally recognized brand names as Colgate, Palmolive, Mennen, Softsoap, Irish Spring, Protex, Sorriso, Kolynos, elmex, Tom’s of Maine, Sanex, Ajax, Axion, Soupline, and Suavitel, as well as Hill’s Science Diet and Hill’s Prescription Diet. For more information about Colgate’s global business, visit the Company’s website at To learn more about Colgate Bright Smiles, Bright Futures®, Colgate’s global oral health education program, please visit

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Saturday, June 22, 2013

Trends in death associated with pediatric dental sedation and general anesthesia

Lee, H. H., Milgrom, P., Starks, H., Burke, W. (2013), Trends in death associated with pediatric dental sedation and general anesthesia. Pediatric Anesthesia. doi: 10.1111/pan.12210



Inadequate access to oral health care places children at risk of caries. Disease severity and inability to cooperate often result in treatment with general anesthesia (GA). Sedation is increasingly popular and viewed as lower risk than GA in community settings. Currently, few data are available to quantify pediatric morbidity and mortality related to dental anesthesia.


Summarize dental anesthesia-related pediatric deaths described in media reports.


Review of media reports in the Lexis-Nexis Academic database and a private foundation website. Settings: Dental offices, ambulatory surgery centers, and hospitals. Patients :US-based children (≤21 years old) who died subsequently receiving anesthesia for a dental procedure between 1980–2011.


Most deaths occurred among 2–5 year-olds (n = 21/44), in an office setting (n = 21/44), and with a general/pediatric dentist (n = 25/44) as the anesthesia provider. In this latter group, 17 of 25 deaths were linked with a sedation anesthetic.


This series of media reports likely represent only a fraction of the overall morbidity and mortality related to dental anesthesia. These data may indicate an association between mortality and pediatric dental procedures under sedation, particularly in office settings. However, these relationships are difficult to test in the absence of a database that could provide an estimate of incidence and prevalence of morbidity and mortality. With growing numbers of children receiving anesthesia for dental procedures from providers with variable training, it is imperative to be able to track anesthesia-related adverse outcomes. Creating a national database of adverse outcomes will enable future research to advance patient safety and quality.

Friday, June 21, 2013

D4D and Henry Schein Launch All-New E4D NEVO Scanner and Design Center for Restorative Dentistry

Enhances Ease-of-Use in Digital Restoration Technology 

RICHARDSON, Texas, June 20, 2013 /PRNewswire/ -- D4D Technologies, LLC, the award-winning developer of digital technologies for dentistry, and Henry Schein, Inc., announced today the all new E4D® NEVO™ Scanner and Design Center, enhancing the ease-of-use in digital dental restorations for the benefit of the patient and the practitioner.
Available exclusively in the U.S., Canada, Australia and New Zealand from Henry Schein, the world's largest provider of health care products and services to office-based dental, medical and animal health practitioners, the E4D NEVO Scanner and Design Center represents a new level of precision, proficiency and productivity versus prior D4D systems.  
The NEVO Scanner technology is based upon years of experience with powder-free image capture in the intraoral environment and is the first scanner to use E4D's patent-pending blue laser technology, which provides exceptional quality of data capture, video-rate speed and ease of use.  The new E4D NEVO Design Center is a powerful laptop computer that uses high-speed Thunderbolt™ technology* with the NEVO Scanner to provide more energy and double the bandwidth of USB 3 connections, resulting in extremely fast processing and alignment of scans. Plug-and-play convenience gives offices of every size the flexibility to customize their E4D NEVO configuration, thereby enhancing the restorative workflow across the entire practice. 
"The E4D NEVO Scanner and Design Center represents what we call the 'Natural EVOlution' of digital dentistry," said Mark Quadling, CEO of D4D Technologies. "We've combined the latest technologies to create an even easier-to-use restoration experience. With NEVO, we believe doctors have the potential to further improve the quality, fit and predictability of restorations, affording the patient a great outcome and strengthening the practitioner's clinical offering."
For example, the NEVO Scanner employs for the first time blue laser technology that features an improved ability to capture the fine details that allow for more precise and accurate prosthetics. The solid-state NEVO Scanner incorporates many other advances to ensure an exceptional intraoral scanning experience. These include fog-free scanning, ergonomic design for easy positioning, removable tips for infection control, active heat dissipation for full arch scanning, color-coded feedback to operator, and adjustable field of view.
The new system features a laptop-based E4D NEVO Design Center, which gives the practitioner increased flexibility and portability. Dentists can easily move the E4D NEVO Design Center from operatory to operatory, or even among multiple offices, all while wirelessly connected to the milling center for maximum productivity and patient service.
"Henry Schein is proud to be the exclusive partner of D4D in bringing this exciting new technology to market," said Tim Sullivan, President, Henry Schein North American Dental Group. "We believe in a patient-centric approach to clinical care, and the new E4D NEVO Scanner and Design Center greatly enhances the benefits of digital dentistry for the patient, which in turn will enhance the practice of our customers. We fully expect that the E4D NEVO system will drive increased demand for digital dentistry, for the new user as well as for those customers who upgrade their systems."
The E4D NEVO Scanner and Design Center will be featured at the E4D Business of Dentistry conference in Las Vegas, August 8-10, 2013 (, and are expected to be available in September.
About D4D Technologies        
Headquartered in Richardson, Texas, D4D Technologies, LLC, is taking the dental profession to a higher level of productivity, patient comfort, and convenience with its E4D restorative systems. E4D's open platform and E4D Sky communication network enable dental professionals to choose a custom solution to fit their needs. E4D offers high-speed laser scanning technology to produce digital 3D impressions of teeth without powder. Intuitive DentaLogic™ software enables operators to easily customize restoration designs and send them wirelessly to the precision mill that uses the latest restorative materials to produce fine esthetic restorations. D4D continues to expand the possibilities in dentistry with E4D Compass™ for restorative-driven implant solutions and E4D Compare™ adaptive learning technology for teaching institutions.  Contact us at or like us at

Thursday, June 20, 2013

Use of glass ionomer cement containing antibiotics to seal off infected dentin: a randomized clinical trial.

Braz Dent J. 2013;24(1):68-73.


Dental materials with antibacterial properties can prevent the harmful effects caused by oral cariogenic bacteria. This double-blind controlled clinical trial evaluated the performance of a glass ionomer cement (GIC) added with antibiotics for sealing infected dentin in atraumatic restorations of primary molars. The study enrolled 45 children (45 teeth) between 5 and 8 years of age, of both genders, divided into two groups: GC (n=22), where cavities were lined with a conventional GIC (Vidrion F) and GA (n=23), with cavities lined with Vidrion F added with 1% each of metronidazole, ciprofloxacin and cefaclor antibiotic. Both groups were restored with Ketac Molar Easymix. Molars with carious lesions on the inner half of dentin without clinical or radiographic pulp damage were selected. Patients were evaluated clinically (pain, fistulas or mobility) and radiographically (area of caries, periapical region and furcation) after 1, 3, 6 and 12 months. For statistical analysis, chi-squared or Fisher's exact tests were used with a 5% significance level. GA (82.6-95.7%) had better results than GC (12.5-36.4%) in all evaluations (p<0 .05="" 46.2-72.5="" and="" antibiotic-containing="" applied="" deciduous="" dentin="" difference="" for="" ga.="" gic="" higher="" in="" infected="" liner="" of="" on="" p="" proved="" rate="" satisfactory="" success="" teeth.="" the="" use="" was="" when="">

Wednesday, June 19, 2013

Five-year results of a prospective randomised controlled clinical trial of posterior computer-aided design–computer-aided manufacturing ZrSiO4-ceramic crowns

Passia, N., Stampf, S. and Strub, J. R. (2013), Five-year results of a prospective randomised controlled clinical trial of posterior computer-aided design–computer-aided manufacturing ZrSiO4-ceramic crowns. Journal of Oral Rehabilitation. doi: 10.1111/joor.12075


The aim of this prospective randomised controlled clinical trial was to evaluate the clinical outcome of shrinkage-free ZrSiO4-ceramic full-coverage crowns on premolars and molars in comparison with conventional gold crowns over a 5-year period. Two hundred and twenty-three patients were included and randomly divided into two treatment groups. One hundred and twenty-three patients were restored with 123 ZrSiO4-ceramic crowns, and 100 patients received 100 gold crowns, which served as the control. All crowns were conventionally cemented with glass–ionomer cement. After an observation period of 6, 12, 24, 36, 48 and 60 months, the survival probability (Kaplan–Meier) for the shrinkage-free ZrSiO4-ceramic crowns was 98·3%, 92·0%, 84·7%, 79% and 73·2% and for the gold crowns, 99%, 97·9%, 95·7%, 94·6% and 92·3%, respectively. The difference between the test and control group was statistically significant (P = 0·0027). The gold crowns showed a better marginal integrity with less marginal discoloration than the ceramic crowns. The most common failure in the ceramic crown group was fracture of the crown. The 60-month results of this prospective randomised controlled clinical trial suggest that the use of these shrinkage-free ZrSiO4-ceramic crowns in posterior tooth restorations cannot be recommended.

Tuesday, June 18, 2013

The nocturnal use of complete dentures and sleep stability in edentulous elders

Available online 8 June 2013



To evaluate the stability of sleep quality and the impact of nocturnal use of complete dentures on sleep quality in an elderly edentulous population over a one-year period.

Materials and methods

Written informed consent was obtained from 172 edentulous elders who agreed to enrol in a longitudinal cohort study. A total of 153 participants completed the follow-up after one year. Perceived quality of sleep and daytime sleepiness were measured using the Pittsburgh Sleep Quality Index (PSQI, score 0-21) and the Epworth Sleepiness Scale (ESS, score 0-24) at baseline (T0) and at follow-up (T1). Data on oral health related quality of life, type of mandibular dentures (conventional versus implant-retained mandibular overdenture), nocturnal wear of the dentures and socio-demographic status were obtained by means of the OHIP-20 questionnaire, a clinical examination form and a socio-demographic questionnaire.


No statistically significant differences were detected in the global PSQI mean scores and EES mean scores from baseline (PSQI 4.77 ± 3.32; EES 5.35 ± 3.72) to the follow-up assessment
(PSQ1 5.04 ± 3.50; EES 5.53 ± 4.34). Edentate elders wearing prostheses at night had poorer daytime sleepiness scores than those who removed their prostheses at night (p= 0.003 unadjusted model; p = 0.058 adjusted for age, gender, type of prosthesis and the OHIP-20 total score).


Results of this study suggest that wearing complete dentures while sleeping has little effect on sleep quality or daytime sleepiness.

Monday, June 17, 2013

Effectiveness of Preventive Dental Visits in Reducing Nonpreventive Dental Visits and Expenditures

Pediatrics Vol. 131 No. 6
pp. 1107 -1113
(doi: 10.1542/peds.2012-2586)


BACKGROUND AND OBJECTIVE: Although preventive dental visits are considered important for maintaining pediatric oral health, there is relatively little research showing that they reduce subsequent nonpreventive dental visits or costs. At least 1 study seemed to find that early preventive dental care is associated with more restorative and emergency visits. Previous studies are limited by their inability to account for unmeasurable factors that may lead children to “select” into using both more preventive and nonpreventive dental care. We used econometric techniques that minimize selection bias to assess the effectiveness of preventive dental care in reducing subsequent nonpreventive dental service utilization among children.
METHODS: Using data from Alabama’s Children’s Health Insurance Program (CHIP), 1998–2010., a cohort study of children’s dental service utilization was conducted. Outcomes were 1-year lagged nonpreventive dental care and expenditures, and overall dental and medical expenditures. Children who were continuously enrolled for at least 3 years were included. Separate models were estimated for children aged <8 em="" years="">n
= 14 972) and those aged ≥8 years (n = 21 833).
RESULTS: More preventive visits were associated with fewer subsequent nonpreventive dental visits and lower nonpreventive dental expenditures for both groups. However, more preventive visits did not reduce overall dental or medical (inclusive of dental) expenditures.
CONCLUSIONS: Preventive dental visits can reduce subsequent nonpreventive visits and expenditures for children continuously enrolled in CHIP. However, they may not reduce overall program costs. Effective empirical research in this area must continue to address unobserved confounders and selection issues.

Saturday, June 15, 2013

Investigation of Biodentine as dentine replacement material

Available online 15 May 2013



Biodentine was compared to glass ionomer and resin modified cements in an “open sandwich” restoration.


Fuji IX, Vitrebond and Biodentine were characterised using various techniques. The effect of etching with 35% phosphoric acid was investigated by assessment of surface topography, Fourier transform infrared (FT-IR) spectroscopy, surface micro-hardness and micro-leakage using tagged carboxylated-modified fluorescent microspheres and tracing the presence of these particles with a confocal microscope.


Acid etching resulted in erosion of the material surface with exposure of the glass particles in the glass ionomer-based materials. Biodentine exhibited a reduction in the chlorine peak and the calcium–silicon ratio. There was no difference in the micro-hardness in etched and un-etched materials. The FT-IR plots did not show any chemical changes caused by etching for all the materials investigated. Both Vitrebond and Fuji IX exhibited no leakage at the dentine to material interface while Biodentine exhibited leakage both when it was etched and also when the surface was left unprepared. The sandwich technique was effective and prevented micro-leakage with glass ionomer-based materials but micro-leakage occurred with Biodentine.


Biodentine demonstrated both structural and chemical changes when etched with 37% phosphoric acid. Biodentine exhibited a lower calcium to silicon ratio and a reduction in the chloride peak height when etched. When used as a dentine replacement material in the sandwich technique overlayed with composite, significant leakage occurred at the dentine to material interface. On the other hand materials based on glass ionomer cement were etched successfully and no chemical and physical changes or micro-leakage were detected when the materials were used as bases under composite restorations. The micro-hardness of all the materials was unaffected by etching.

Friday, June 14, 2013

I am not the only one who thinks that Dr. Oz can cause more harm then good

Dr. Oz may know his cardiologist but he sure does not know a thing about dentistry. Previous Dr. Oz dental debacles include bleaching your teeth with lemon juice and preventing gum disease through drinking cranberry juice. He continues the ineptitude by weighing in on the use of amalgam.

So here is a great link to an article in Forbes magazine calling out Dr. Oz for his failure to look at the facts. I think the real facts are that Dr. Oz is now more about entertainment then health care.

Dr. Oz Is Worried About Your Teeth. Should You Worry Too?

Thursday, June 13, 2013

Fatigue Behavior of the Resinous Cement to Zirconia Bond

 Seto, K. B., McLaren, E. A., Caputo, A. A. and White, S. N. (2013), Fatigue Behavior of the Resinous Cement to Zirconia Bond. Journal of Prosthodontics. doi: 10.1111/jopr.12053



Resinous cements are widely used for luting zirconia restorations. Adhesive failures have occurred at the cement/zirconia interface, rather than at the cement/dentin interface, suggesting that the cement/zirconia bond may lack durability; however, few comprehensive, comparative evaluations of fatigue effects have been reported. The rate of fatigue-induced loss of bond strength may be a more important predictor of long-term success than a single snapshot of bond strength after an arbitrary number of thermocycles. Previous studies have failed to identify trends by investigating bond strengths at several different numbers of cycles. This may result in invalid conclusions about which cements have superior bond strengths. The purpose of this study was to investigate the effects of artificial aging by thermocycling and resinous cement type on bond strengths to zirconia.

Materials and Methods

The effect of the number of thermocycles (0, 1, 10, 100, 1000, and 10,000) on the bond strengths of five resinous cements, two of which were used with and without a primer, and an oxygen-inhibiting gel, was studied. Specimens were randomly assigned to thermocycle number/cement-type test groups. Because zirconia has a very low thermal diffusivity, exceptionally long thermocycle dwell times were used. Cylinders of zirconia were bonded end-to-end. One end of each bonded specimen was insulated, specimens were thermocycled and tested in shear, and bond strengths were calculated and analyzed.


Two-way ANOVA revealed that the effects of cement type, the number of thermocycles, and their interaction all significantly affected bond strength (p < 0.0001). By 10,000 cycles, most cements had lost at least half of their initial bond strengths, and two cements effectively recorded zero bond strengths. Failure modes were cement specific, but adhesive modes predominated. Fatigue resistance of two cements was greatly improved by use of a primer and an oxygen-inhibiting gel, as recommended by their respective manufacturers.


Both the type of resin cement and the number of thermocycles influenced bond strength. Fatigue through thermocycling affected different cement types in different ways. Some materials displayed more rapid loss of bond strength than others. Cements differed in their failure modes.

Wednesday, June 12, 2013

Microleakage of Teeth Restored with Different Adhesive Dowel Systems: An In Vitro Study

Sarı, T. and Özyesil, A. G. (2013), Microleakage of Teeth Restored with Different Adhesive Dowel Systems: An In Vitro Study. Journal of Prosthodontics. doi: 10.1111/jopr.12054



Commercial fiber-reinforced dowel systems are marketed as having better adhesion and sealing ability than conventional metallic dowel systems. The aim of this in vitro study was to evaluate the microleakage of teeth restored with nine dowel systems.

Materials and Methods

Ninety mandibular second premolar teeth were decoronated, and nine homogenous groups were composed of ten teeth each. Root canal and dowel space preparations were made, and eight fiber-reinforced composite dowel systems and one stainless steel dowel system were used to fabricate dowel restorations. Microleakage measurements of the restored teeth were made with a modified fluid filtration method, and data were collected. One sample Kolmogorov-Smirnov, one-way ANOVA, and Tukey-HSD tests were performed on the relative microleakage data of the groups.


Microleakage values were reported relative to those for teeth with unfilled canals. The highest and lowest relative microleakage values were recorded for the metallic Parapost (7.06 × 10−4%) and fiber-reinforced Everstick (3.55 × 10−4%) groups, respectively. Significant differences in relative microleakage between the fiber-reinforced dowels and stainless steel dowels were observed. Significant differences among the fiber-reinforced dowel groups were observed as well.


The sealing ability of all fiber-reinforced composite dowels is not better than that of stainless steel dowels, and there are significant differences among different fiber-reinforced dowel systems as well. Differences among commercial dowel systems must be taken into consideration when making a selection.

Tuesday, June 11, 2013

New Sirona Materials Expand Clinical Indications for CEREC

New innovations from Sirona improve anterior esthetics, implant surgical procedures and introduce high-strength zirconia to direct, chairside applications for the dentist

CHARLOTTE, N.C. – June 11, 2013 – Sirona Dental, Inc., the technology leader in the dental industry, announced today the release of three new high-performance materials that deliver superior esthetics, enhanced strength and expand the breadth of CEREC.

The new materials include: 1) chairside millable blocks that mimic the tooth’s natural internal chromatic dentin layer under a translucent incisal surface to improve anterior esthetics, 2) a new intraoral scan body that simplifies implant procedures and eliminates physical impressions and models, and 3) a high-strength zirconia material ideal for any posterior restorative situation, including second molars.

Achieve Ultimate Esthetics with CEREC C In Blocs
The interaction between chromatic dentin and the translucent incisal area in the visible anterior tooth region has previously been a limiting factor for the use of CAD/CAM systems.  With Sirona’s new CEREC C In Blocs, this is no longer the case.

CEREC C In Blocs consist of an inner core of highly chromatic dentin-like ceramic covered by a translucent layer of ceramic that mimics natural enamel. The dentin cores are modeled after the shape of dentin in natural teeth, while the outer shape of the tooth is determined by the patented Biogeneric process in the CEREC software guaranteeing a perfect anatomical fit. Additional software algorithms correctly and automatically position the restoration in the block, so that the exact tooth color selected by the user is achieved and an aesthetically-pleasing, most lifelike restoration is possible.

In-House Implant Restoration Made Easier With ScanPost
The digital workflow for chairside implant restorative cases has never been easier. With the new ScanPost, the implant axis is simply and quickly defined with a quick scan from CEREC AC with Omnicam or CEREC AC with Bluecam. By providing all relevant data about implant position, ScanPost eliminates the need for a poured model and placement of implant analogs in the conventional lab process.  While screw retained to the implant, ScanPost stays above the gingival margin, allowing users to verify that the scan body is fully and properly seated, even in the most sub gingival placement of implants. This adds even more user confidence in the chairside process, resulting in easier and reliable intraoral scanning and predictable outcomes every time. Once the position of the implant is determined by the CEREC software, the user then completes the implant case in a few simple steps.


T  h  e     D  e   n  t  a  l      C  o   m  p  a  n  y
inCoris TZI – High-Strength, Full Contour Zirconium Oxide Restorations for Chairside Application
Full contour Zirconia is ideal for indications that demand the perfect combination of high-strength and lifelike, patient-pleasing esthetics. Thanks to its high degree of translucency, inCoris TZI does not require any veneering materials, making it a cost-effective substitute for metal, porcelain fused to metal or two-part all-ceramic crowns. inCoris TZI is now available for CEREC chairside users.

Benefits of inCoris TZI include:
·         Highly translucent zirconium oxide for full crowns and bridges
·         Less reduction needed in most clinical cases
·         Can be milled with select CEREC® milling units [does this mean MC XL units? If so, better to simply say “Can be milled with any CEREC MC XL milling unit”]
·         Approved for speed (90 minute sintering) and superspeed (10 minute sintering) cycles with inFire HTC speed
All Sirona inFire HTC speed sintering furnaces can process inCoris TZI within 90 minutes. However, with the recently launched superspeed process, the inCoris TZI material may be sintered in just 10 minutes, bringing full contour zirconia into the chairside workflow for the first time. The inFire unit achieves significantly better energy efficiency through shorter heating and cooling times and the timer function allows economical sintering overnight.

“These new products are designed with our users and their patients in mind,” said Sirona Vice President of CAD/CAM Roddy MacLeod.  “We’re bringing extraordinary technology to the dentist, continuing our commitment to improve the patient experience and practice lifestyle.”

For more information about CEREC or to schedule a free in-office demonstration please visit or call your local Patterson sales representative at 800.873.7683.

About Sirona Dental, Inc.
Sirona, the dental technology leader, has served dealers and dentists worldwide for more than 130 years. Sirona develops, manufactures and markets a complete line of dental products, including CAD/CAM restoration systems (CEREC), digital intra-oral, panoramic and 3D imaging systems, dental treatment centers and handpieces. Visit for more information about Sirona and its products.

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Bond Strength of the Porcelain Repair System to All-Ceramic Copings and Porcelain

Lee, S. J., Cheong, C. W., Wright, R. F. and Chang, B. M. (2013), Bond Strength of the Porcelain Repair System to All-Ceramic Copings and Porcelain. Journal of Prosthodontics. doi: 10.1111/jopr.12064



The purpose of this study was to investigate the shear bond strength of the porcelain repair system on alumina and zirconia core ceramics, comparing this strength with that of veneering porcelain.

Materials and Methods

Veneering ceramic (n = 12), alumina core (n = 24), and zirconia core (n = 24) blocks measuring 10 × 5 × 5 mm3 were fabricated. Veneering ceramic blocks were used as the control. Alumina and zirconia core blocks were divided into 2 groups (n = 12 each), and a slot (2 × 2 × 4 mm3) filled with veneering ceramics was prepared into one of the alumina and zirconia core groups (n = 12). Followed by surface treatments of micro-abrasion with 30 μm alumina particles, etching with 35% phosphoric acid and silane primer and bond, composite resin blocks (2 × 2 × 2 mm3) were built up and light polymerized onto the treated surfaces by 3 configurations: (a) composite blocks bonded onto veneering ceramic surface alone, (b) composite blocks bonded onto alumina core or zirconia core surfaces, (c) a 50% surface area of the composite blocks bonded to veneering ceramics and the other 50% surface area of the composite blocks to alumina core or zirconia core surfaces. The shear bond strength of the composite to each specimen was tested by a universal testing machine at a 0.5 mm/min crosshead speed. The shear bond strength was analyzed by unpaired t-tests for within the configuration groups and ANOVA for among the different configuration groups.


When the mean shear bond strength was compared within groups of the same configuration, there were no statistically significant differences. Comparison of the shear bond strength among groups of different configurations revealed statistically significant differences. The mean shear bond strength of composite onto 100% veneering ceramic surface and composite onto 50% veneering 50% all-ceramic cores was statistically higher than that of composite onto 100% all-ceramic cores; however, the differences of the shear bond strength of composite bonded only onto the veneering ceramic surface were not statistically significant from those of 50% surface area of composite bonded onto all-ceramic cores.


No statistically significant differences in the bond strength of a porcelain repair system to alumina and zirconia copings were observed. Increasing the surface of veneering ceramics to a porcelain repair system improved the repair material's bond strength.

Monday, June 10, 2013

Kerr Launches Nexus RMGI to Help Dentists “Speed Up the Cleanup” and Much More

ORANGE, CA –June 4, 2013 – Kerr Corporation, a leading manufacturer of innovative dental restorative materials, has announced the launch of its new NexusTM RMGI, a unique dental cement that combines One-PeelTM cleanup, outstanding durability, and improved esthetic qualities for consistent, predictable outcomes. 

As the first RMGI on the market available with advanced Nexus Technology, Kerr’s Nexus RMGI provides an optimal gel state and 2–3 second tack cure capability to ensure easy One-Peel cleanup with every use. The product’s self-adhesive paste/paste dual adhesive technology also delivers significantly higher bond, compressive and flexural strengths, which provide improved durability and marginal integrity. Further, Nexus RMGI’s BPO-free and Amine-free chemistry combines for optimum translucency with exceptional color stability. 

Delivered in a convenient automix syringe, Nexus RMGI is designed to provide the dentist with a new standard for cementation of metal-based restorations including full-color zirconia.
“We’ve repeatedly heard from our clinical customers about the deficiencies that exist with current RMGI dental cements on the market today, such as unpredictability of clean-up times, low bond strength, and less than desirable appearance,” said Alistair Simpson, Kerr’s Vice President of Marketing. “Nexus RMGI addresses these deficiencies while providing a convenient delivery system. The superior esthetics further differentiates the product, especially with so many of today’s dental practices utilizing zirconia.” 

Kerr Product Manager, Nick Domanico added that Nexus RMGI is now ready for distribution and will be shipping to customers this month. 

Kerr Corporation, manufactures, markets and sells premier dental consumables to dental professionals worldwide.
Kerr, Nexus and One-Peel are trademarks of Kerr Corporation.

Saturday, June 08, 2013

Red Dot Design Awards Honor Two 3M ESPE Solutions

3M™ ESPE™ Intra-oral Syringe and 3M™ ESPE™ Retraction Capsule are recognized

ST. PAUL, Minn. – (June 4, 2013) – 3M ESPE has again received honors at the prestigious Red Dot Design Awards, with recognition in 2013 for the 3M™ ESPE™ Intra-oral Syringe and the 3M™ ESPE™ Retraction Capsule. The Red Dot Design Awards are considered one of the world’s most distinguished design competitions, and this year more than 4,662 products were entered for consideration.
In the competition, international design experts rated nominees based on criteria including degree of innovation, functionality, self-explanatory quality and ecological soundness. 3M ESPE’s winning products exemplify the company’s technical strength and commitment to solving problems for customers through innovative design:
·      The single-use intra-oral syringes for VPS and polyether impression materials are designed for precise application of wash materials in the patient’s mouth. The syringes were recognized for a high degree of innovation, functional and ergonomic design, ease of use and longevity.
·      The retraction capsule is an ergonomic dispenser for astringent retraction paste that allows for effective mechanical retraction of the gingiva prior to impression-taking or direct restorative procedures. The retraction capsule is compatible with common composite dispensers, and enables easy application directly into the sulcus due to its very fine tip.

Both products will receive the Red Dot Quality Seal during the awards ceremony in Essen, Germany on July 1.
“3M ESPE has a long history of design innovations that improve the delivery of products,” said Mark Farmer, president, 3M ESPE. “We are honored to be recognized once again for creating highly functional solutions that make dentistry easier for our customers and their patients.”
3M ESPE has previously received Red Dot honors for its Scotchbond™ Universal Adhesive, Elipar™ S10 LED Curing Light and Pentamix™ 3 Automatic Mixing Unit.
For more information about the intra-oral syringe, visit
For more information about the retraction capsule, visit