Cone-beam Computed Tomography Compared with Intraoral Radiographic Lesions in Endodontic Outcome Studies: A Systematic Review
Highlights
- •This systematic review qualified and quantified CBCT in endodontic outcome.
- •Six articles met the inclusion criteria with low to moderate risk of bias. The certainty of evidence was high.
- •CBCT is twice as likely to detect a lesion compared to traditional radiography.
Abstract
Introduction
The
 purpose of this systematic review was to compare and quantify 
endodontic outcome using cone-beam computed tomographic (CBCT) imaging 
with intraoral periapical radiography.
Methods
Two
 reviewers independently conducted a comprehensive literature search. 
The MEDLINE, Embase, Cochrane, and PubMed databases were searched. 
Additionally, bibliographies, gray literature of all relevant articles, 
and textbooks were manually searched. There was no disagreement between 
the 2 reviewers.
Results
Six
 articles met the inclusion criteria with low to moderate risk of bias 
(good/fair quality). The certainty of evidence was moderate, indicating 
that the authors are moderately confident that the true effect lies 
close to that of the estimate of the effect as determined by Grading of 
Recommendations Assessment Development and Evaluation criteria. The odds
 ratio of CBCT imaging versus traditional imaging to detect a periapical
 lesion was 2.04 (95% confidence interval, 1.52–2.73).
Conclusions
Although
 intraoral radiographs are the imaging modality of choice, when 
2-dimensional intraoral radiography is inconclusive, CBCT imaging was 
reported in this investigation to have twice the odds of detecting a 
periapical lesion than traditional periapical radiography in endodontic 
outcome studies.

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