Clinical Research Randomized controlled clinical trial of digital and conventional workflows for the fabrication of zirconia-ceramic fixed partial dentures. Part III: Marginal and internal fit
The Journal of Prosthetic Dentistry
Available online 3 November 2018
Abstract
Statement of problem
Trials comparing the overall performances of digital and conventional workflows in restorative dentistry are lacking.
Purpose
The
 purpose of the third part of this clinical study was to test whether 
the fit of zirconia 3-unit frameworks for fixed partial dentures 
fabricated with fully digital workflows differed from that of metal 
frameworks fabricated with the conventional workflow.
Material and methods
In
 each of 10 participants, 4 fixed-partial-denture frameworks were 
fabricated for the same abutment teeth according to a randomly generated
 sequence. Digital workflows were applied for the fabrication of 3 
zirconia frameworks with Lava, iTero, and Cerec infiniDent systems. The 
conventional workflow included a polyether impression, manual waxing, 
the lost-wax technique, and the casting of a metal framework. The 
discrepancies between the frameworks and the abutment teeth were 
registered using the replica technique with polyvinyl siloxane. The dimensions of the marginal discrepancy (Discrepancymarginal) and the internal discrepancy in 4 different regions of interest (Discrepancyshoulder, Discrepancyaxial, Discrepancycusp, and Discrepancyocclusal) were assessed using a light microscope. Post hoc t tests with Bonferroni correction were applied to detect differences (α=.05).
Results
Discrepancyshoulder
 was 96.1 ±61.7 μm for the iTero, 106.9 ±96.0 μm for the Lava, 112.2 
±76.7 μm for the Cerec infiniDent, and 126.5 ±91.0 μm for the 
conventional workflow. The difference between the iTero and the 
conventional workflow was statistically significant (P=.029). Discrepancyocclusal
 was 153.5 ±66.8 μm for the iTero, 203.3 ±127.9 μm for the Lava, 179.7 
±63.1 μm for the Cerec infiniDent, and 148.8 ±66.8 μm for the 
conventional workflow. Discrepancyocclusal was significantly lower for the conventional workflow than for the Lava and the Cerec infindent workflows (P<.01). The iTero resulted in significantly lower values of Discrepancyocclusal than the Lava and the Cerec infiniDent workflows (P<.01).
Conclusions
In
 terms of framework fit in the region of the shoulder, digitally 
fabricated zirconia 3-unit frameworks presented similar or better fit 
than the conventionally fabricated metal frameworks. In the occlusal 
regions, the conventionally fabricated metal frameworks achieved a more 
favorable fit than the CAD-CAM zirconia frameworks.

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