Minimally-invasive non-surgical approach for the treatment of periodontal intrabony defects: a retrospective analysis.

J Clin Periodontol. 2015 Aug 10. doi: 10.1111/jcpe.12443. [Epub ahead of print]



The aim of this retrospective analysis was to assess healing of intrabony defects treated with minimally-invasive non-surgical therapy (MINST).


A retrospective analysis was carried out in 35 consecutive intrabony defects treated by MINST (without any adjuncts) in 23 non-smoking patients. All defects had a radiographic intrabony component > 3 mm and had clinical and radiographic data available at baseline and 12 after treatment. Pre- and post-treatment radiographs were analyzed and bone levels were compared by multilevel linear regression adjusted by latent variable method.


Following MINST, the average PPD and CAL reduction in the intrabony defects were 3.12 mm and 2.78 mm respectively (p<0 .001="" 2.93="" 28.5="" 3.81="" 44.35="" 6.74="" and="" angle="" angles="" associated="" at="" average="" baseline="" by="" change.="" changed="" deeper="" defect="" depth="" depths="" from="" greater="" initial="" intrabony="" less="" mm="" p="" radiographic="" re-evaluation="" reduced="" reduction.="" smaller="" the="" to="" vertical="" was="" were="" while="" with="">


This paper shows considerable clinical and radiographic improvements after MINST, therefore bringing evidence to support its efficacy for the treatment of intrabony defects in non- smokers.