Effect of a chlorhexidine/thymol and a fluoride varnish on caries development in erupting permanent molars: a comparative study
Abstract
Aim
To
compare the caries preventive effect of a
chlorhexidine/thymol-containing antibacterial varnish with a fluoride
varnish when topically applied during the eruption of permanent molars.
Methods
The
study group consisted of 189 patients, 5–14 years of age, with one 1st
or 2nd permanent molar in the process of eruption. After stratification
for type of molar and stage of eruption, the patients were randomised to
either quarterly topical applications with an antibacterial varnish
(Cervitec® Plus; CV group) or biannual applications with a
fluoride varnish plus biannual treatments with placebo varnish (Fluor
Protector; FV group). The duration of the study was 2 years. The primary
endpoint was caries incidence (initial and cavitated) in the erupting
molars and the secondary outcome was salivary mutans streptococci (MS)
counts.
Results
The
groups were balanced with respect to socio-economy, oral hygiene,
dietary habits and caries experience at baseline. The dropout rate was
11.6 %. The caries incidence was low (<10 0.94="" 1.08="" 95="" and="" at="" between="" both="" caries="" ci="" class="EmphasisTypeItalic" cv="" development="" difference="" disclosed="" em="" end="" erupting="" fv="" group="" groups="" in="" levels="" lower="" molars="" ms="" nbsp="" no="" occlusal="" of="" relative="" respect="" risk="" salivary="" significant="" significantly="" study="" the="" there="" to="" was="" were="" with="">p
Conclusions
No
difference in occlusal caries development in young permanent molars was
displayed after topical applications of either a chlorhexidine/thymol
varnish or a fluoride varnish during tooth eruption.
Comments