Study Shows OraCoat® XyliMelts® Oral Adhering Discs Effectively Treat Acid Reflux

FDA-Approved Clinical Trial Shows that XyliMelts Discs are an Effective Supplement for Treating Many Acid Reflux Symptoms

Bellevue, WA (December 1, 2016) – A recent study revealed that OraCoat® XyliMelts® oral-adhering discs greatly reduce symptoms of heartburn in acid reflux sufferers. The double-blinded, randomized, placebo-controlled study conducted by Peter Van der Ven, DMD, PhD; Jeffrey Burgess, DDS, MSD; and Michael Karcher, BA, PhD candidate; was approved by the Western Institutional Review Board and the U.S. Food and Drug Administration (FDA).

Gastro-esophageal reflux disease (GERD), more commonly known as acid reflux, describes a chronic digestive condition in which an accumulation of stomach acid in the esophagus creates symptoms. Acid reflux affects about 30 percent of the population on a weekly basis and is known to contribute to or cause a number of medical and dental problems including heartburn, sore throat, laryngitis, cough, halitosis, and tooth decay. The condition is also associated with sleep disturbance and can have a negative effect on nighttime comfort and overall quality of life.

The study aimed to prove if XyliMelts, recently rated by a Clinicians Report® survey as the most effective remedy for alleviating dry mouth could produce similar results in treating patients suffering from acid reflux, which is often managed by prescribed and over-the-counter medications that prevent excessive acid production. XyliMelts are formulated from all-natural ingredients commonly used in foods. As tests prove that salivary stimulants can decrease the perception of nighttime dry mouth, tests also suggest increased saliva can diminish nighttime reflux.

Conducted over two weeks, the study analyzed 53 test subjects who provided daily responses to nine questions listing common acid reflux symptoms that might have occurred during the prior night’s sleep. The subjects were separated into two groups, with 26 administered with XyliMelts discs delivered in unmarked packaging, while 27 subjects received the placebo treatment, a water-based gel packaged in an unmarked white tube. Neither the research coordinator nor the subjects were aware which product was being used for data collection.

Test results displayed that both the disc and gel reduced the taste of reflux, heartburn sensation, morning hoarseness, perceived reflux severity, and the number of antacids taken during the night. While both groups demonstrated comparable effectiveness in combating most symptoms, XyliMelts exhibited a profoundly higher improvement rate in lessening heartburn intensity than the placebo gel.*

Overall, the study supports the use of XyliMelts discs as a supplemental remedy for counteracting symptoms during sleep in acid reflux patients.* The discs were well tolerated by all the subjects involved with no adverse reactions reported.

To learn more about XyliMelts and for additional information on other OraCoat brand products, please visit

*Documentation of these statements available upon request.

Survey of 1168 dentists, March 2016 Clinicians Report®, an independent, non-profit, dental education and product testing foundation. The full report is available on

About OraCoat division of OraHealth Corporation

OraCoat is the world leader in the breakthrough technology of “oral adhering discs” which slowly release ingredients in the mouth and are safe for use while sleeping. The OraCoat® brand represents a family of products that solve oral care problems by coating the mouth with safe ingredients that become effective when they are slowly released. Our flagship product is XyliMelts® for Dry Mouth, a dietary supplement. Other oral care solutions in the OraCoat family are planned. OraCoat’s innovative oral care solutions are backed by careful research based on medical science to ensure optimum performance and user safety.

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