Abstract
This article presents the results of a consecutive case series of 170
treated peri-implantitis-affected implants in 100 patients with
follow-up measurements from 2 to 10 years. A total of 51 implants in 38
patients previously reported on were followed for an additional 2.5
years, and 119 additional implants in 62 additional patients were
treated with the same protocol and monitored for at least 2 years
posttreatment. The treatment consisted of flap reflection, surface
decontamination, use of enamel matrix derivative (EMD) or
platelet-derived growth factor (PDGF), and guided bone regeneration with
mineralized freezedried bone and/or anorganic bovine bone combined with
PDGF or EMD and covered with an absorbable membrane and/or
subepithelial connective tissue graft. Maintenance and monitoring
followed every 2 to 3 months. Two implants were lost 6 months
posttreatment, for a 98.8% survival rate. Bleeding on probing was
eliminated in 91% of the treated implants. Probing depth reduction
averaged 5.10 mm, bone level gain averaged 1.77 mm, and soft tissue
marginal gain averaged 0.52 mm. These outcomes were obtained with one
surgical procedure on 140 implants, with two procedures on 18 implants,
and with three procedures on 10 implants. The results to date with this
layered/combined regenerative approach for the treatment of
peri-implantitis appear to be encouraging.
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