Cochrane Review Confirms Clinical Benefits of Triclosan/Copolymer Formula in Colgate Total® Toothpaste
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New York, NY (February
21, 2014)
- Triclosan/copolymer, the
antibacterial active system employed in Colgate Total® toothpaste
for preventing plaque and gingivitis, recently received a very positive independent
review. The review was conducted by the Cochrane Oral Health Group which carries out systematic reviews of primary research in human
healthcare and health policy that are internationally recognized as the highest
standard in evidence-based healthcare.
Entitled “Triclosan/copolymer containing toothpastes for oral
health,” the Cochrane Review evaluated the effects of triclosan/copolymer
containing fluoride toothpastes, as compared to traditional fluoride
toothpastes, for the long-term control of caries, plaque and gingivitis in both
children and adults.
The Cochrane Review evaluated 30 studies dating from 1990 to 2012
in which 14,835 participants
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were randomized to receive either a triclosan/copolymer containing
fluoride toothpaste or a traditional fluoride toothpaste that did not contain
triclosan/copolymer. The toothpaste used in the studies containing the
triclosan/copolymer system and fluoride was Colgate Total®.
The resulting data highlighted the many clinical benefits of using
a triclosan/copolymer containing fluoride toothpaste and concluded there was no
evidence of any harmful effects associated with the use of triclosan/copolymer
toothpastes.
Some key findings of the Cochrane Review include:
·
After six or more months of use, fluoride toothpaste containing triclosan/copolymer
provided a 22% reduction in plaque as compared with traditional
fluoride toothpaste. It also provided a 41%
reduction in plaque severity as
compared with traditional fluoride toothpaste.
·
After six or more months of use, fluoride toothpaste containing triclosan/copolymer
provided a 22% reduction in gingivitis
compared with traditional fluoride toothpaste. It provided a 48% reduction in gum bleeding compared with traditional
fluoride toothpaste.
“I commend
the Cochrane Oral Health Group for taking the time to conduct a rigorous review
of the clinical studies performed on the fluoride toothpaste containing triclosan/copolymer,”
remarked Dr. Fotinos S.
Panagakos, Global
Director, Scientific Affairs and Research Relations for the Colgate-Palmolive
Company. “I have no doubt that this noteworthy review will draw further attention
to the topic of gum disease, which is a prevalent oral health issue. The most
recent national health and nutrition examination survey (NHANES) showed that 3
out of 4 US adults have experienced gum bleeding, which is a sign of gingivitis,
an early form of gum disease. If left untreated, gingivitis can lead to periodontitis,
a more serious form of gum disease with multiple potential harmful health
effects. This is one of the many reasons that I feel that gum disease deserves
a significant amount of time and attention. I am pleased to confirm that
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one of our
most noteworthy contributions to helping to combat this disease is our
introduction of the triclosan/copolymer system to fluoride toothpaste, which is
found in our line of Colgate Total® toothpastes.”
For the full
text of the Cochrane Review, please visit
For more
information about all Colgate Total® products, please visit www.colgateprofessional.com.
About The Cochrane Oral Health Group
The Cochrane Oral
Health Group comprises an international network of healthcare
professionals, researchers and consumers preparing, maintaining and
disseminating systematic reviews
of randomized controlled trials
in oral health. The Oral Health
Group is one of 53 review groups around the world belonging to The Cochrane
Collaboration: an international non-profit and independent organization,
providing up-to-date evidence-based information about the effects of specific healthcare
intervention on health outcomes. For more information, please visit www.us.cochrane.org.
About Colgate Oral Pharmaceuticals
Colgate
Oral Pharmaceuticals is a subsidiary of Colgate-Palmolive, a consumer products
company, and a leader in the oral care market with both over-the-counter and
therapeutic professional products. For more information, please visit www.colgateprofessional.com.
About Colgate-Palmolive
Colgate-Palmolive
is a leading global consumer products company, tightly focused on Oral
Care, Personal Care, Home Care and Pet Nutrition. Colgate sells its products in
over 200 countries and territories around the world under such internationally
recognized brand names as Colgate, Palmolive, Mennen, Softsoap, Irish Spring,
Protex, Sorriso, Kolynos, elmex, Tom’s of Maine, Sanex, Ajax, Axion, Soupline,
and Suavitel, as well as Hill’s Science Diet and Hill’s Prescription Diet. For
more information about Colgate’s global business, visit the Company’s website
at http://www.colgatepalmolive.com.
To learn more about Colgate Bright Smiles, Bright Futures®, Colgate’s
global oral health education program, please visit www.colgatebsbf.com.
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