A practice-based study on the effect of a short sucrose/xylitol exposure on survival of primary teeth caries free
ANTTONEN, V., HALUNEN, I., PÄKKILÄ, J., LARMAS, M. and TJÄDERHANE, L.
(2011), A practice-based study on the effect of a short sucrose/xylitol
exposure on survival of primary teeth caries free. International Journal
of Paediatric Dentistry. doi: 10.1111/j.1365-263X.2011.01205.x
Background. In a randomized double-blinded clinical trial, preschool children used sucrose or xylitol chewing gum regularly for 2 months to study the preventive effect of xylitol on acute otitis media (AOM). Salivary mutans streptococci (sm) levels of the children were measured before the exposure. Those with ≥105sm CFU in 1 mL saliva were considered to have high sm levels (sm+); and those with <105 CFU low sm levels (sm−).
Background. In a randomized double-blinded clinical trial, preschool children used sucrose or xylitol chewing gum regularly for 2 months to study the preventive effect of xylitol on acute otitis media (AOM). Salivary mutans streptococci (sm) levels of the children were measured before the exposure. Those with ≥105sm CFU in 1 mL saliva were considered to have high sm levels (sm+); and those with <105 CFU low sm levels (sm−).
Aim. This practice-based study aims to evaluate long-term dental effects of the sucrose/xylitol exposure on primary teeth.
Design. For analyses, individuals were divided into sub groups according to their study group in the original AOM trial and baseline sm
levels. Outcome events owing to dental caries of their all primary
teeth were followed from dental records up to 12 years. Survival of
teeth caries free was determined by Kaplan–Meier method and analysed
statistically by Wilcoxon testing.
Results. Survival of primary teeth caries free of children with high sm levels in the sucrose group was significantly shorter compared with all other groups when followed until shedding.
Conclusions. Two months’ regular exposure to sucrose was sufficient to induce dental caries in primary teeth of children with elevated sm levels at baseline.
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