Tooth Repair and Regeneration


Open Access
Dental Stem Cells in Tissue Regeneration (F Setzer, Section Editor)

Part of the following topical collections:
  1. Topical Collection on Dental Stem Cells in Tissue Regeneration

 

Abstract

Purpose of Review

Current dental treatments are based on conservative approaches, using inorganic materials and appliances.
This report explores and discusses the newest achievements in the field of “regenerative dentistry,” based on the concept of biological repair as an alternative to the current conservative approach.

Recent Findings

The review covers and critically analyzes three main approaches of tooth repair: the re-mineralization of the enamel, the biological repair of dentin, and whole tooth engineering.

Summary

The development of a concept of biological repair based on the role of the Wnt signaling pathway in reparative dentin formation offers a new translational approach into development of future clinical dental treatments.
In the field of bio-tooth engineering, the current focus of the researchers remains the establishment of odontogenic cell-sources that would be viable and easily accessible for future bio-tooth engineering.

Keywords

Regenerative dentistry Dentinogenesis Bio-tooth Biological repair Reparative dentin 

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