Comparison of pulp response to mineral trioxide aggregate and a bioceramic paste in partial pulpotomy of sound human premolars: a randomized controlled trial
Abstract
Aim
This
randomized clinical trial evaluated clinical sign/symptoms as well as
histological pulp reactions in terms of inflammation and mineralized
bridge formation after partial pulpotomy of sound human premolars and
placement of a bioceramic Paste (iRoot BP) or tooth-colored ProRoot MTA
as pulp covering biomaterials.
Methodology
Twenty
four human sound premolars were randomly allocated into two
experimental groups (n=12) either treated with iRoot BP or MTA
subsequent to partial pulpotomy treatment. Six weeks after treatment,
clinical sign/symptoms and radiographic changes were evaluated. The
teeth were then extracted and examined histologically for inflammatory
status of the pulp, formation of hard tissue bridge, and appearance of
the bridge In terms of pulp inflammation and dentinal bridge formation
the Mann–Whitney U and for clinical signs Chi square tests were used (α =
0.05).
Results
In
terms of pulp inflammation, formation of hard tissue bridge and its
appearance the differences between the two experimental groups were not
significant. However, clinical sensitivity to cold was significantly
less for teeth treated with MTA (p<0 .05="" a="" all="" and="" bridge="" cases="" either="" formed="" group="" had="" hard="" in="" necrosis.="" none="" of="" p="" pulpal="" specimens="" the="" tissue="">
Conclusion
When
treating teeth with healthy pulps, the response to partial pulpotomy
treatment with both MTA and iRoot BP was favourable. However,pulps
covered with iRoot BP were more sensitive to cold stimuli.
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