Abstract
Aim:
 To evaluate the outcome of immediately loaded mandibular cross-arch 
prostheses according to the 'all-on-4' concept supported by implants 
placed in fresh extraction sockets up to 18 months after loading. 
Materials and methods: In total, 47 patients with a mean age of 62.3 
years (range 52 to 78) were rehabilitated with an immediately loaded 
fixed cross-arch prosthesis supported by four post-extractive implants. A
 total of 188 implants were inserted. Patients received a provisional 
fixed dental prosthesis with a metal framework within 48 hours after 
surgery and a permanent one 6 months later. The patients were evaluated 
clinically and radiographically at implant placement and at 6-, 12- and 
18-month follow-up examinations. Results: At the 18-month follow-up, no 
implant failed and all restorations were stable. Peri-implant bone 
levels amounted to 0.31 ± 0.12 mm after 6 months, 0.58 ± 0.112 mm after 
12 months and 0.7 ± 0.107 mm after 18 months. No significant differences
 in bone loss were found between axially placed and tilted implants at 
the 6-month (0.06 mm; P = 0.115), the 12-month (0.12 mm; P = 0.062) and 
the 18-month follow-up (0.08 mm; P = 0.146). Three patients had a 
fracture of the provisional restoration, but all of the definitive 
prostheses remained stable throughout the study period without any 
complications. Conclusions: Within the limits of this study, it can be 
suggested that immediately loaded mandibular cross-arch fixed dental 
prostheses can be supported by four post-extractive implants, however 
larger and longer follow-ups are needed.
 
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