The Effect of Ozone alone and in combination with adjunct remineralisation products on Inhibition of Demineralisation of the Dental Hard Tissues. in situ
Abstract
Objectives
In
the United Kingdom Ozone therapy combines the use of ozone gas and
adjunct products called reductant and the patient kit, which all contain
fluoride. We studied the effect of these products with and without the
use of ozone in inhibiting demineralisation of human enamel and dentine
under a cariogenic challenge in situ.
Methods
A
single-blind, randomised, three legs, cross-over study design was used.
Fourteen volunteers were provided with a lower removable intra-oral
appliance carrying one enamel and one dentine slabs. Baseline
measurements of enamel and dentine hardness slabs were recorded. The
study regime of 14 days of dipping into 10% sucrose solution five times a
day was applied. The three legs were two test groups
Ozone/Reductant/Patient Kit, Reductant/Patient Kit, and a Fluoride free
toothpaste group as a control. At the end of the 2nd week the slabs were collected, microhardness measured and the differences from the baselines were calculated.
Results
There
were statistically significant differences in the mean changes of
enamel and dentine hardness when both test groups were compared
individually with the control. However, no statistical significant
differences in either parameter was found when Ozone/Reductant/Patient
Kit group was compared with Reductant/Patient Kit treatment.
Conclusions
We
conclude from these results that ozone had no additional effect on the
inhibition of enamel and dentine demineralisation than when
Reductant/Patient Kit, containing high concentrations of Fluoride, were
used on their own.
Comments