Comparison of the effect of endodontic-periodontal combined lesion on the outcome of endodontic microsurgery with that of isolated endodontic lesion: survival analysis using propensity score analysis
Abstract
Objectives
The
purpose of this retrospective clinical study was to evaluate the effect
of lesion types related to endodontic microsurgery on the clinical
outcome.
Materials and methods
Patients
who underwent endodontic microsurgery between March 2001 and March 2014
with a postoperative follow-up period of at least 1 year were included
in the study. Survival analyses were conducted to compare the clinical
outcomes between isolated endodontic lesion group (endo group) and
endodontic-periodontal combined lesion group (endo-perio group) and to
evaluate other clinical variables. To reduce the effect of selection
bias in this study, the estimated propensity scores were used to match
the cases of the endo group with those of the endo-perio group.
Results
Among
the 414 eligible cases, the 83 cases in the endo-perio group were
matched to 166 out of the 331 cases in the endo group based on
propensity score matching (PSM). The cumulated success rates of the endo
and endo-perio groups were 87.3 and 72.3%, respectively. The median
success period of the endo-perio group was 12 years (95% CI: 5.507,
18.498). Lesion type was found to be significant according to both
Log-rank test (P = 0.002) and Cox proportional hazard regression analysis (P = 0.001).
Among the other clinical variables, sex (female or male), age, and
tooth type (anterior, premolar, or molar) were determined to be
significant in Cox regression analysis (P < 0.05).
Conclusion
Endodontic-periodontal
combined lesions had a negative effect on the clinical outcome based on
an analysis that utilized PSM, a useful statistical matching method for
observational studies.
Clinical relevance
Lesion type is a significant predictor of the outcome of endodontic microsurgery.
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