University of California, Irvine Study Shows OraCoat® XyliMelts® discs reduce plaque by over 50%
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Study Demonstrated that OraCoat XyliMelts Effectively
Improve Many Symptoms of Dry Mouth Including the Ability to Eat and Swallow
Bellevue,
WA (March 22, 2017) – Researchers at the University of California, Irvine analyzed
the effects of OraCoat® XyliMelts® oral adhering discs on
people affected by clinically diagnosed dry mouth. The double-blind, randomized
study demonstrated that XyliMelts reduce tooth plaque by 58% and improve the
ability to eat and swallow in those affected by dry mouth.
Dry mouth is the subjective sensation of
oral dryness that affects up to 60% of the elderly population, and is caused by
various disorders and oral cancer treatments such as radiation to the head and
neck. Additionally, a number of medications, including over-the-counter drugs
such as antidepressants, decongestants, antihistamines, appetite suppressors,
and diuretics produce symptoms of dry mouth. Dry mouth symptoms include a
sticky, dry sensation in the mouth, tongue roughness, frequent liquid
consumption, difficulty speaking and swallowing, and sleep disruption.
OraCoat XyliMelts is a patented
dry mouth product that sticks to the gums on the outside of a molar, releasing
one-half gram of Xylitol, which stimulates saliva, and cellulose gum which,
combined with saliva, forms a lubricating gel. Xylitol, slowly released in the
mouth so it lingers, is effective for reducing dry mouth and tooth decay. Moreover,
XyliMelts used at night while sleeping when saliva flow is lowest is the most
effective delivery of Xylitol.*
The 21-day clinical study evaluated in patients
with dry mouth the effects of XyliMelts on saliva production and ability to
neutralize acids, as well as patient comfort. The study was administered to five
test subjects who used XyliMelts as recommended: two discs while sleeping, one
on each side of the mouth, and as needed during the day. On average, the
subjects used four discs each day during daytime hours.
Test results showed the clinical usefulness
of XyliMelts for effectively relieving dry mouth. Researchers found that
XyliMelts significantly reduced sleep disruption by lasting for six hours while
sleeping, when dry mouth is at its worst, while improving mouth wetness upon
waking in the morning. XyliMelts also diminished tooth sensitivity to hot,
cold, and spicy foods and drinks. The adhering discs more than doubled saliva
production while in place, and increased the ability of saliva to neutralize
acids that cause tooth decay. Most importantly, the test displayed that
subjects using XyliMelts in conjunction with standard oral care showed heightened
saliva flow compared to standard oral care alone. XyliMelts not only alleviates
symptoms of dry mouth, they also stimulate saliva production.
Overall, subject feedback to XyliMelts was positive,
with subjects stating that they would continue using the discs while
recommending them to others. Subjects also reported XyliMelts as easy to use
with a favorable taste and overall mouth feel.
The study was published on February 13,
2017, and can be found here.
In a March 2016 Clinicians Report® survey of dentists published by CR
Foundation, an independent, non-profit, dental education and product testing
foundation, 152 dentists who were familiar with OraCoat XyliMelts rated it more
effective than any other remedy for dry mouth, including prescription drugs
which came in second.†
XyliMelts are
available over the counter at CVS and Rite Aid. For more information on
XyliMelts, visit www.oracoat.com. Consumers
interested in receiving a free sample (limit one per household) should call
1-855-275-4766.
A companion product to OraCoat XyliMelts
for oral cancer patients is OraCoat XyliGel®, a soothing gel with
17% Xylitol buffered to pH 7.4 to relieve dry mouth. It works especially well
for people with very low levels of saliva. XyliGel is available online at oracoat.com.
*Documentation
of these statements available upon request.
†Survey of 1168 dentists, March 2016 Clinicians Report®, an independent, non-profit, dental
education and product testing foundation.
About OraCoat
OraCoat is a
division of OraHealth Corporation, the world
leader in the breakthrough technology of “oral adhering discs” which slowly
release ingredients in the mouth and are safe for use while sleeping.
The OraCoat® brand represents a family of products that solve oral care
problems by coating the mouth with safe ingredients that become effective when they are slowly
released. Our flagship product is XyliMelts® for Dry Mouth, an OTC product. Other oral care solutions in
the OraCoat family are planned. OraCoat’s innovative oral care
solutions are backed by careful research based on medical science to ensure
optimum performance and user safety.
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