Abstract
AIM:
to
evaluate the adjunctive clinical efficacy of probiotics in the
treatment of peri-implant mucositis (p-iM) with professionally
administered plaque removal (PAPR) and photodynamic therapy (PDT).
MATERIALS AND METHODS:
Following
p-iM induction, patients underwent PAPR+PDT and were randomly assigned
to receive the professional and home-based administration of probiotics
(Lactobacillus plantarum and Lactobacillus brevis) (test treatment) or
placebo preparation (control treatment) according to a cross-over
design. Clinical parameters were assessed at 6 sites for each implant
before as well as at 2 and 6 weeks after professional treatment
administration.
RESULTS:
Twenty
patients contributing 1 dental implant each were included. Immediately
before treatment and at 6 weeks, the median number of sites with
bleeding on probing (BoP+) sites per implant unit was 4 (3-6) and 2
(0-2) (p< 0.001), respectively, for test treatment, and 3.5 (2-4) and
2 (0-3) (p= 0.03), respectively, for control treatment. No significant
difference in clinical outcomes was observed between treatment groups.
CONCLUSION: The combination of PAPR and PDT either alone or associated with
probiotics determined a significant reduction of the number of BoP+
sites at 2 and 6 weeks around implants with p-iM. The adjunctive use of
probiotics did not significantly enhance the clinical outcomes of PAPR +
PDT.
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