purpose of this prospective, randomized, double-blind study was to
compare the anesthetic efficacy of buffered with nonbuffered 2%
lidocaine with 1:80,000 epinephrine solution for inferior alveolar nerve
(IAN) block in patients with mandibular posterior teeth experiencing
symptomatic irreversible pulpitis.
adult patients diagnosed with symptomatic irreversible pulpitis of a
mandibular posterior tooth were selected. The patients received 2
cartridges of either 2% lidocaine with 1:80,000 epinephrine buffered
with 0.18 mL 8.4% sodium bicarbonate or 2% lidocaine with 1:80,000
epinephrine with 0.18 mL sterile distilled water using conventional IAN
block injections. Endodontic access preparation was initiated 15 minutes
after injection. Lip numbness was required for all the patients.
Success was determined as no or mild pain on the basis of Heft-Parker
visual analog scale recordings upon access cavity preparation or initial
instrumentation. Data were analyzed by the t, Mann-Whitney, and chi-square tests.
success rates were 62.5% and 47.5% for buffered and nonbuffered groups,
respectively, with no significant differences between the two groups (P = .381).
the 2% lidocaine with 1:80,000 epinephrine with 8.4% sodium bicarbonate
did not improve the success of the IAN block in mandibular molars in
patients with symptomatic irreversible pulpitis.