Dentsply Sirona Launches AI Integration with Pearl
This seamless integration of DS Core, Dentsply Sirona’s cloud-based platform, with Second Opinion, Pearl’s chairside dental AI software, is aimed at enhancing 2D X-ray radiologic accuracy and patient communication.

Dentsply Sirona, the world’s largest diversified manufacturer of dental products and solutions, and Pearl, a leader in dental AI solutions, announced today a partnership to deliver AI-assisted 2D X-ray radiologic support through DS Core¹. This collaboration empowers dental professionals with enhanced radiologic capabilities and supports more informed patient conversations.
The integration enables automatic exchange of 2D X-ray data between DS Core and Second Opinion chairside dental AI software. This allows dentists to utilize AI-driven insights to help them identify anatomical structures and detect issues such as early-stage cavities or bone loss. These findings support the dentist’s clinical expertise during treatment planning and presentation. The AI also generates visualizations with automated annotations and measurements, which serve as compelling tools for patient education and help improve treatment acceptance.
“This collaboration with Dentsply Sirona brings our vision of accessible, trustworthy dental AI to an even broader global audience,” said Ophir Tanz, CEO of Pearl. “By embedding Second Opinion directly into DS Core, we’re giving clinicians seamless access to AI insights that strengthen their diagnostic confidence, improve patient communication, and ultimately elevate the standard of care across every practice.”
“Our goal is to foster an open, collaborative ecosystem where innovation thrives. With its open architecture, DS Core empowers partners and developers to build integrated solutions that streamline diagnosis, enhance patient outcomes, and optimize clinical workflows,” said Max Milz, Group VP of Connected Technology Solutions at Dentsply Sirona. “Following the launch of our own AI-powered 3D X-ray capabilities on DS Core, this integration marks another important step toward making advanced diagnostics more accessible and connected—underscoring our commitment to seamless workflows and better care through shared progress.”
DS Core API
The integration is made possible by Dentsply Sirona’s newly released DS Core API (Application Programming Interface). The API provides a comprehensive set of rules and protocols that allow third-party providers, PMS, labs, and DSOs to connect their software applications with DS Core for enhanced and efficient workflows.
With continuously expanding documentation and capabilities, the DS Core API allows developers to easily configure their systems for integration, ensuring that dental professionals can leverage DS Core’s advanced features alongside their existing software solutions.
For more information on DS Core API, please visit: https://open.dscore.com/
REFERENCE
- The availability of the announced products and features will be market-dependent. Please reach out to a local Dentsply Sirona representative for more information.
About Dentsply Sirona
Dentsply Sirona is the world’s largest diversified manufacturer of professional dental products and technologies, with over a century of innovation and service to the dental industry and patients worldwide. Dentsply Sirona develops, manufactures, and markets a comprehensive solutions offering including dental and oral health products as well as other consumable medical devices under a strong portfolio of world-class brands.
Dentsply Sirona’s innovative products provide high-quality, effective, and connected solutions to advance patient care and deliver better and safer dental care. Dentsply Sirona’s headquarters is located in Charlotte, North Carolina. The Company’s shares are listed in the United States on Nasdaq under the symbol XRAY.
Visit www.dentsplysirona.com for more information about Dentsply Sirona and its products.
About Pearl
Pearl is the global leader in dental AI, advancing oral healthcare with tools that elevate diagnostic accuracy, workflow efficiency, and practice performance. Founded in 2019, Pearl delivers the industry’s broadest AI product suite—from chairside detection to enterprise intelligence—built in collaboration with providers, practice managers, and leading dental institutions. Its flagship solution, Second Opinion, is FDA-cleared for patients aged 4 and older and holds more regulatory clearances—including in 120 countries—than any other dental AI. With innovations like Practice Intelligence, Precheck, and the first FDA-cleared 3D dental AI, Pearl is shaping a smarter, more trusted future for dentistry worldwide. To learn more, visit hellopearl.com.
DISCLAIMER
This information and any attachments thereto contain “forward-looking statements” within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Such statements are not guarantees of future performance. These forward-looking statements reflect views and assumptions regarding expectations and projections about future events and are based on currently available information or information available on the date of any document incorporated by reference. You can generally identify these forward-looking statements by the use of words such as “may,” “could,” “estimate,” “will,” “believe,” “anticipate,” “think,” “intend,” “expect,” “project,” “plan,” “target,” “forecast,” and similar words and expressions. However, these words are not the exclusive means of identifying such statements.
In addition, any statements that refer to expectations, projections, or other characterizations of future events or circumstances are forward-looking statements and may include statements relating to future revenues, expenses, margins, profitability, net income/(loss), earnings per share, and other measures of results of operations and the prospects of future growth of our business. These forward-looking statements are inherently subject to uncertainties, risks, and changes in circumstances that are difficult to predict. For a discussion of such risks, uncertainties, and other matters that could cause actual results to differ materially, including risks relating to, among other factors, the market for dental products and services, pricing, future sales volume of the Company’s products, the possibility of changing economic, market, and competitive conditions, dependence on products, dependence on key personnel, technological developments, intense competition, market uncertainties, dependence on distributors, ability to manage growth, dependence on key suppliers, dependence on key members of management, government regulation, our ability to integrate the businesses of Dentsply Sirona, acquisitions and affiliations, readers are urged to carefully review and consider various disclosures made by the Company and Dentsply Sirona in their public filings, including in their Annual Reports on Form 10-K and in their reports on Forms 10-Q and 8-K filed with the Securities and Exchange Commission.
Readers are cautioned not to place undue reliance on such statements, which speak only as of the date hereof. Except as required by law, the Company does not assume any obligation to update any forward-looking statements contained in this document or the attachments to reflect new information or future events or developments after the date any such statement is made.
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