Clinical and radiographic evaluation of platelet-rich fibrin for revascularization of necrotic immature permanent teeth: A controlled clinical trial
Pediatric Dental Journal
Abstract
Background
Ideal management of necrotic immature permanent teeth to close the blunderbuss apical opening still of challenge and debate.
Objective
clinical and radiographic evaluation of platelet rich fibrin (PRF) for revascularization of necrotic immature permanent teeth.
Method
28 single-rooted necrotic immature permanent teeth from 28 children (7–13 years old) assigned into two main groups (contaminated and uncontaminated). Teeth of each group divided randomly into two subgroups according to type of treatment; PRF subgroup (experimental) and calcium hydroxide apexification subgroup (control). Clinical and radiographic evaluations assessed at baseline, 3, 6, and 9 months.
Results
all subgroups showed clinical success of 100%. Radiographic results presented a significant difference in all intervals regarding root length, diameter of apical foramen and radiographic root area (RRA) in PRF subgroups. Regarding root length, significant difference was for PRF subgroup at 3rd interval in group I. Diameter of apical foramen showed significant differences for PRF subgroups at 2nd and 3rd intervals. RRA revealed significant differences for PRF subgroups in both groups at 2nd and 3rd intervals.
Conclusions
platelet-rich fibrin revascularization and calcium hydroxide apexification were successful clinically. Radiographically, platelet-rich fibrin showed significant quantitative measurements than calcium hydroxide apexification regarding all parameters.
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