In situ remineralizing effect of fluoride varnishes containing sodium trimetaphosphate
May 2015
Abstract
Objective
This
study analyzed the effects of a fluoride (F) varnish supplemented with
sodium trimetaphosphate (TMP) on the remineralization of caries-like
lesions in situ.
Materials and methods
Twelve
subjects used palatal devices with demineralized enamel discs for
3 days, following a double-blind, crossover protocol. Test groups
included placebo (no F or TMP), 5 % NaF and 5 % NaF/5 % TMP varnishes.
The percentage of surface hardness recovery (%SHR) and cross-sectional
hardness (ΔKHN) were determined.
Results
Significant
differences were observed among all varnishes regarding %SHR and ΔKHN.
The highest %SHR and the lowest ΔKHN were seen for the 5 % NaF/5 % TMP
varnish, followed by 5 % NaF and placebo.
Conclusion
The remineralizing effect of a 5 % NaF varnish is significantly enhanced when associated with TMP.
Clinical relevance
The
reduction in the subsurface lesion area of enamel treated with the
TMP-containing varnish implies that cavities would take longer to
develop or might not develop at all depending on individual factors,
resulting in lower net caries increments at individual and population
levels.
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