aim of this multicentre, parallel-group randomized clinical trial was
to compare the effectiveness of mineral trioxide aggregate (MTA) and a
conventional calcium hydroxide liner (CH) as direct pulp capping
materials in adult molars with carious pulpal exposure.
adults aged 18–55 years were randomly allocated to two parallel arms:
MTA (White ProRoot, Dentsply, Tulsa Dental, Tulsa, OK, USA; n = 33) and CH (Dycal®, Dentsply DeTrey GmbH, Konstanz, Germany; n = 37).
The teeth were temporized for 1 week with glass–ionomer (Fuji IX, GC
Corp, Tokyo, Japan) and then permanently restored with a composite
resin. The subjects were followed up after 1 week and at six, 12, 24 and
36 months. The primary outcome was the survival of the capped pulps,
and the secondary outcome was postoperative pain after 1 week. Survival
was defined as a nonsymptomatic tooth that responded to sensibility
testing and did not exhibit periapical changes on radiograph. At each
check-up, the pulp was tested for sensibility and a periapical
radiograph was taken (excluding the radiographs taken at the 1-week
follow-up). Kaplan–Meier survival analysis and log-rank test were used
to assess the significant difference in the survival curves between
groups. Chi-square test was used to assess the association between the
materials and preoperative and postoperative pain.
36 months, the Kaplan–Meier survival analysis showed a cumulative
estimate rate of 85% for the MTA group and 52% for the CH group (P = 0.006). There was no significant association between the capping material and postoperative pain.
trioxide aggregate performed more effectively than a conventional CH
liner as a direct pulp capping material in molars with carious pulpal
exposure in adult patients. This study has been registered at
ClinicalTrials.gov, number NCT01224925.