Monday, June 15, 2015

Effect of a chlorhexidine/thymol and a fluoride varnish on caries development in erupting permanent molars: a comparative study

Abstract

European Archives of Paediatric Dentistry

Aim

To compare the caries preventive effect of a chlorhexidine/thymol-containing antibacterial varnish with a fluoride varnish when topically applied during the eruption of permanent molars.

Methods

The study group consisted of 189 patients, 5–14 years of age, with one 1st or 2nd permanent molar in the process of eruption. After stratification for type of molar and stage of eruption, the patients were randomised to either quarterly topical applications with an antibacterial varnish (Cervitec® Plus; CV group) or biannual applications with a fluoride varnish plus biannual treatments with placebo varnish (Fluor Protector; FV group). The duration of the study was 2 years. The primary endpoint was caries incidence (initial and cavitated) in the erupting molars and the secondary outcome was salivary mutans streptococci (MS) counts.

Results

The groups were balanced with respect to socio-economy, oral hygiene, dietary habits and caries experience at baseline. The dropout rate was 11.6 %. The caries incidence was low (<10 0.94="" 1.08="" 95="" and="" at="" between="" both="" caries="" ci="" class="EmphasisTypeItalic" cv="" development="" difference="" disclosed="" em="" end="" erupting="" fv="" group="" groups="" in="" levels="" lower="" molars="" ms="" nbsp="" no="" occlusal="" of="" relative="" respect="" risk="" salivary="" significant="" significantly="" study="" the="" there="" to="" was="" were="" with="">p
 < 0.05).

Conclusions

No difference in occlusal caries development in young permanent molars was displayed after topical applications of either a chlorhexidine/thymol varnish or a fluoride varnish during tooth eruption.

No comments: